Powerful RetinOil Next-Gen

Products containing retinol or retinoids must not be used during pregnancy, breastfeeding, or when planning pregnancy. Consult your doctor before use.

Store the product at room temperature (up to +25 °C) in a dry place, protected from direct sunlight.

Avoid contact with mucous membranes and eyes. Do not apply retinoid products to the mobile eyelid.

To support skin recovery after retinoid use, apply SuperBiotic Regenerating Cream or HydraFusion Hydrating Gel Cream. These products help maintain balance, reduce irritation risk, and enhance retinoid efficacy. After using retinoids in your morning or daytime routine, always apply sunscreen SPF 50.

Products containing acids and retinoids may cause temporary redness or irritation — this is an individual skin response.

INSTYTUTUM formulas contain a high concentration of active ingredients. To minimize the risk of irritation, introduce new products gradually, starting with 2–3 times per week.

Recommendations are based on the use of products within the INSTYTUTUM range. Combining with products from other brands may increase sensitivity and lead to unpredictable reactions.

If you plan to use acids and retinol together, start with acids 2–3 times per week, and after 10–14 days, if no irritation occurs, add retinoid-based products; in case of an adverse reaction, discontinue use of the active product for 2–5 days and then reintroduce it gradually.

When starting products with active ingredients (retinol, acids, vitamin C), the skin may temporarily react with breakouts, flaking, or irritation — this is a purging phase that indicates the activation of cellular renewal and detoxification; it usually appears 2–3 weeks after beginning active ingredients and can last up to 9–10 weeks, and during this time it’s important not to drastically change your routine and allow the skin to adapt, but if the condition worsens significantly or the reaction does not subside, consult a dermatologist or skincare professional.