Refillable
New
Advanced Barrier & Microbiome Regeneration
132.00 €
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Advanced Barrier & Microbiome Regeneration
Calms the skin and visibly reduces redness in just 15 minutes
Reduces skin sensitivity by 70% in 4 weeks
Restores and strengthens the skin barrier

Superbiotic Refill Set is an advanced skin recovery duo in a convenient refill format, featuring the full-size Superbiotic Regenerating Cream and a Refill POD. This science-backed system targets the root causes of skin concerns—not just the visible symptoms. Powered by INSIDE & OUT Technology, the formula preserves the potency of active ingredients while restoring the skin barrier and rebalancing the skin microbiome—the key triggers of inflammation, redness, and premature skin aging.
This Set Is Ideal If
Your skin shows signs of a compromised barrier, including dryness, irritation, redness, or flaking.
Your skin needs recovery after acids, retinoids, chemical peels, or intensive aesthetic treatments.
Your skin is reactive, hypersensitive, or prone to rosacea-like redness.
You're looking for an SOS treatment or preventive care during periods of increased skin sensitivity.
You want to restore radiance, firmness, and comfort without causing irritation.
Why Choose Superbiotic Refill Set?
Targets the Root Cause – Works beyond the surface by restoring the skin barrier and microbiome while activating the skin's natural regeneration processes.
Multi-Functional Moisturizer – Perfect as a day cream, night cream, or post-procedure recovery treatment—one formula for every stage of your skincare routine.
Designed to Complement Active Ingredients – The ideal companion to acids, retinoids, and professional exfoliating treatments, helping minimize dryness, flaking, and irritation.
Clinically Proven Performance – 9 out of 10 users reported improved skin elasticity, smoothness, and overall skin condition within just one week.
Suitable for Sensitive Skin – Fragrance-free formula developed with dermatologically tested ingredients for optimal skin tolerance.
Refill POD – Helps you continue your skincare ritual while reducing environmental impact with a more sustainable refill system.
Results: Skin feels deeply hydrated, comfortable, and visibly more elastic, with reduced redness and sensitivity. The microbiome is rebalanced, the skin barrier is strengthened, and the complexion looks healthier, calmer, and more radiant—even under daily environmental stress—with Superbiotic Refill Set.
Superbiotic Refill Set is an advanced skin recovery duo in a convenient refill format, featuring the full-size Superbiotic Regenerating Cream and a Refill POD. This science-backed system targets the root causes of skin concerns—not just the visible symptoms. Powered by INSIDE & OUT Technology, the formula preserves the potency of active ingredients while restoring the skin barrier and rebalancing the skin microbiome—the key triggers of inflammation, redness, and premature skin aging.
This Set Is Ideal If
Your skin shows signs of a compromised barrier, including dryness, irritation, redness, or flaking.
Your skin needs recovery after acids, retinoids, chemical peels, or intensive aesthetic treatments.
Your skin is reactive, hypersensitive, or prone to rosacea-like redness.
You're looking for an SOS treatment or preventive care during periods of increased skin sensitivity.
You want to restore radiance, firmness, and comfort without causing irritation.
Why Choose Superbiotic Refill Set?
Targets the Root Cause – Works beyond the surface by restoring the skin barrier and microbiome while activating the skin's natural regeneration processes.
Multi-Functional Moisturizer – Perfect as a day cream, night cream, or post-procedure recovery treatment—one formula for every stage of your skincare routine.
Designed to Complement Active Ingredients – The ideal companion to acids, retinoids, and professional exfoliating treatments, helping minimize dryness, flaking, and irritation.
Clinically Proven Performance – 9 out of 10 users reported improved skin elasticity, smoothness, and overall skin condition within just one week.
Suitable for Sensitive Skin – Fragrance-free formula developed with dermatologically tested ingredients for optimal skin tolerance.
Refill POD – Helps you continue your skincare ritual while reducing environmental impact with a more sustainable refill system.
Results: Skin feels deeply hydrated, comfortable, and visibly more elastic, with reduced redness and sensitivity. The microbiome is rebalanced, the skin barrier is strengthened, and the complexion looks healthier, calmer, and more radiant—even under daily environmental stress—with Superbiotic Refill Set.
Plant-Derived Ceramides – restore the skin barrier, lock in moisture, and improve resilience against external aggressors.
3% Prebiotic & Probiotic Complex – rebalances the skin microbiome, helps protect cells from glycation (one of the major causes of premature skin aging), and restores healthy-looking radiance.
Albatrellus Mushroom, Evening Primrose Oil & Panthenol (Provitamin B5) – rapidly reduce visible signs of skin sensitivity, including redness, itching, and tightness.
Dermochlorella & Brown Algae Extract – strengthen the skin's microvascular network, support cellular renewal, and promote a more even-looking complexion.
AQUA/WATER/EAU, GLYCERIN, COCO-CAPRYLATE, SORBITAN STEARATE, PROPANEDIOL, SACCHAROMYCES/XYLINUM/BLACK TEA FERMENT, ARGANIA SPINOSA KERNEL OIL, PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL, CETYL ALCOHOL, PRUNUS ARMENIACA (APRICOT) KERNEL OIL, BUTYROSPERMUM PARKII (SHEA) BUTTER, OENOTHERA BIENNIS (EVENING PRIMROSE) OIL, SQUALANE, DECYL OLEATE, PANTHENOL, ALPHA-GLUCAN OLIGOSACCHARIDE, CHONDRUS CRISPUS (CARRAGEENAN) EXTRACT, SODIUM POLYGLUTAMATE, HIPPOPHAE RHAMNOIDES FRUIT EXTRACT, ANNONA CHERIMOLA FRUIT EXTRACT, ALBATRELLUS CONFLUENS (MUSHROOM) EXTRACT, PHOSPHOLIPIDS, CHLORELLA VULGARIS EXTRACT, UNDARIA PINNATIFIDA EXTRACT, SPHINGOLIPIDS, ROSA CENTIFOLIA FLOWER EXTRACT, ROSA DAMASCENA FLOWER OIL, ROSA DAMASCENA FLOWER WATER, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, PANTOLACTONE, ASCORBYL PALMITATE, LECITHIN, XANTHAN GUM, TOCOPHEROL, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, SODIUM HYDROXIDE, SODIUM CITRATE, BIOSACCHARIDE GUM-1, CITRIC ACID, PHENYLPROPANOL, HYDROGENATED PALM GLYCERIDES CITRATE, PENTYLENE GLYCOL, CARBOMER, PHENETHYL ALCOHOL, PHENOXYETHANOL, DISODIUM EDTA, ETHYLHEXYLGLYCERIN, POTASSIUM SORBATE, POTASSIUM BENZOATE, SODIUM BENZOATE, SODIUM DEHYDROACETATE, BLUE 1 (CI 42090).
Components
Plant-Derived Ceramides – restore the skin barrier, lock in moisture, and improve resilience against external aggressors.
3% Prebiotic & Probiotic Complex – rebalances the skin microbiome, helps protect cells from glycation (one of the major causes of premature skin aging), and restores healthy-looking radiance.
Albatrellus Mushroom, Evening Primrose Oil & Panthenol (Provitamin B5) – rapidly reduce visible signs of skin sensitivity, including redness, itching, and tightness.
Dermochlorella & Brown Algae Extract – strengthen the skin's microvascular network, support cellular renewal, and promote a more even-looking complexion.
AQUA/WATER/EAU, GLYCERIN, COCO-CAPRYLATE, SORBITAN STEARATE, PROPANEDIOL, SACCHAROMYCES/XYLINUM/BLACK TEA FERMENT, ARGANIA SPINOSA KERNEL OIL, PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL, CETYL ALCOHOL, PRUNUS ARMENIACA (APRICOT) KERNEL OIL, BUTYROSPERMUM PARKII (SHEA) BUTTER, OENOTHERA BIENNIS (EVENING PRIMROSE) OIL, SQUALANE, DECYL OLEATE, PANTHENOL, ALPHA-GLUCAN OLIGOSACCHARIDE, CHONDRUS CRISPUS (CARRAGEENAN) EXTRACT, SODIUM POLYGLUTAMATE, HIPPOPHAE RHAMNOIDES FRUIT EXTRACT, ANNONA CHERIMOLA FRUIT EXTRACT, ALBATRELLUS CONFLUENS (MUSHROOM) EXTRACT, PHOSPHOLIPIDS, CHLORELLA VULGARIS EXTRACT, UNDARIA PINNATIFIDA EXTRACT, SPHINGOLIPIDS, ROSA CENTIFOLIA FLOWER EXTRACT, ROSA DAMASCENA FLOWER OIL, ROSA DAMASCENA FLOWER WATER, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, PANTOLACTONE, ASCORBYL PALMITATE, LECITHIN, XANTHAN GUM, TOCOPHEROL, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, SODIUM HYDROXIDE, SODIUM CITRATE, BIOSACCHARIDE GUM-1, CITRIC ACID, PHENYLPROPANOL, HYDROGENATED PALM GLYCERIDES CITRATE, PENTYLENE GLYCOL, CARBOMER, PHENETHYL ALCOHOL, PHENOXYETHANOL, DISODIUM EDTA, ETHYLHEXYLGLYCERIN, POTASSIUM SORBATE, POTASSIUM BENZOATE, SODIUM BENZOATE, SODIUM DEHYDROACETATE, BLUE 1 (CI 42090).
Transformation with INSTYTUTUM
Individual results may vary. The photos are without any retouching. All results are from actual product use.
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Q&A
SuperBiotic Regenerating Cream differs from classic moisturizers in that it has a unique formula for restoring the skin's microbiome, enriched with ceramides and a complex of pre- and probiotics. The active ingredients help strengthen the skin barrier, reduce reactivity, instantly reduce redness, and provide comprehensive care and relief for sensitive and reactive skin.
Yes, the cream is ideal for skin undergoing a course of retinoids or acids, as it strengthens the skin barrier, restores the microbiome, and minimizes the risk of flaking, irritation, or sensitivity after active procedures.
Yes, SuperBiotic Cream can be used as a single skincare product: it deeply moisturizes the skin, especially if its barrier is compromised or needs SOS repair.
The complex of pre- and probiotics helps restore the healthy balance of the skin's microbiome, strengthens barrier functions, and reduces sensitivity and susceptibility to irritation, redness, and inflammatory reactions, increasing the skin's resistance to negative environmental effects.
Yes. Thanks to its light texture and balanced composition, the cream restores and moisturizes the skin without leaving a greasy shine and does not clog pores, making it effective for oily and combination skin.
Yes, SuperBiotic Cream is compatible with active ingredients such as vitamin C, retinol, or acids. The cream reduces the risk of irritation, flaking, and dryness. We recommend using the cream in your evening routine after active serums to maintain comfort and restore the skin.

Superbiotic Refill Set
Quantity: 1