Clinically tested

−3 years in calculated skin biological age on average, in 3 months*

Before / Initial Condition

Before / Initial Condition

After / 84 days

After / 84 days

Biological skin age is not the same as chronological age; it is a measurable condition of the skin

In a study of the INSTYTUTUM comprehensive skincare routine, the calculated skin's biological age*

–3 years

in 3 months*

A measured reduction in the calculated skin's biological age over 84 days.

*Based on an 84-day clinical study of the full 7-product INSTYTUTUM AM/PM routine among 21 women aged 35–60. The claimed reduction in “skin biological age” is a calculated age equivalent based solely on periocular (crow’s feet) wrinkle depth measurement and does not constitute a medical or comprehensive assessment of biological age. Individual results may vary.

Discover Longevity Skincare
Discover Longevity Skincare

100% of participants noted visible results and comfort from the routine*

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    100% — improved hydration

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    100% — smoother skin and a more even texture

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    100% — enhanced radiance

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    100% — daily skin comfort

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    100% — full adherence to all steps of the routine

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    100% — comfort and tolerability of the Eye Cream

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    100% — improved skin tone and texture with the Glow Toner

94.9% — average percentage of positive ratings for additional results*

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    95,2% — improvement in elasticity

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    95,2% — radiance and even skin tone with Vitamin C Serum

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    95,2% — effectiveness and tolerability of Retinol Serum

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    95,2% — recovery and comfort with Superbiotic Cream

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    93,6% — willingness to continue using the routine on average throughout the study

*Based on the participants’ assessments of changes in skin condition on day 84 and the average values for days 28, 56, and 84 of the study “Clinical and Instrumental Evaluation of the Effectiveness of the INSTYTUTUM Skincare Routine.”

100% of participants noted visible results and comfort from the routine*

Longevity Skincare, designed to reduce the skin's biological age*

INSTYTUTUM's Comprehensive Routine: 7 products. 8 steps. 84 days. Clinically proven results.

*Based on an 84-day open-label clinical-instrumental study conducted under the supervision of a dermatologist at an independent European laboratory evaluating the full 7-product INSTYTUTUM AM/PM skincare routine (Adaptogel Cleanser, Resurfacing Glow Toner, Brightening Vitamin C Serum, X-Strength Retinol Serum, Sunscription Dark Spot Defence SPF50, Superbiotic Regenerating Cream, and Transforming Brightening Eye Cream, each applied as directed) among 21 female participants aged 35–60 (skin phototypes I–IV) with visible signs of chrono- and/or photo-ageing. The claimed reduction in calculated skin biological age reflects an average age equivalent derived solely from 3D profilometry measurements of periocular (crow’s feet) wrinkle depth compared to the testing laboratory’s reference correlation database for women aged 30–65. This constitutes an aesthetic calculation based on a single parameter, not a medical, biological, or comprehensive assessment of overall skin or bodily ageing. Individual results may vary; in the study, not all participants showed a reduction in periocular wrinkle depth. “Longevity Skincare” describes the product category and formulation approach of the INSTYTUTUM range and is not a claim of any effect on lifespan, cellular ageing, or physiological ageing processes. Full study documentation is available for regulatory authorities upon request. Individual results may vary. The photos are without any retouching. All results are from actual product use.