–11.7% reduction in wrinkle depth in the “crow’s feet” area*
–11.7%
over 84 days
*Based on an 84-day clinical study of the full 7-product INSTYTUTUM AM/PM routine among 21 women aged 35–60.
Clinically proven

Before / Initial Condition

After / 84 days
*Based on an 84-day clinical study of the full 7-product INSTYTUTUM AM/PM routine among 21 women aged 35–60.
-11,7%
reduction in wrinkle depth in the “crow's feet” area*
+9%
skin elasticity R2*
+16,2%
skin elasticity R0*
100%
participants noticed an improvement in skin smoothness and texture*
In a study of the INSTYTUTUM comprehensive skincare routine, the calculated skin's biological age decreased by 3 years as measured by the depth of periorbital wrinkles*
–3 years
in 3 months*
A measured reduction in the calculated skin's biological age over 84 days.
*Based on an 84-day clinical study of the full 7-product INSTYTUTUM AM/PM routine among 21 women aged 35–60. The claimed reduction in “skin biological age” is a calculated age equivalent based solely on periocular (crow’s feet) wrinkle depth measurement and does not constitute a medical or comprehensive assessment of biological age. Individual results may vary.
Each checkpoint in the study confirmed further improvement in key markers of skin youthfulness
–11.7%
over 84 days
*Based on an 84-day clinical study of the full 7-product INSTYTUTUM AM/PM routine among 21 women aged 35–60.
Elasticity R2
Firmness R0
100% — improved hydration
100% — smoother skin and a more even texture
100% — enhanced radiance
100% — daily skin comfort
100% — full adherence to all steps of the routine
100% — comfort and tolerability of the Eye Cream
100% — improved skin tone and texture with the Glow Toner
95,2% — improvement in elasticity
95,2% — radiance and even skin tone with Vitamin C Serum
95,2% — effectiveness and tolerability of Retinol Serum
95,2% — restoration and comfort with Superbiotic Cream
93,6% — willingness to continue using the routine on average throughout the study
*Based on the participants’ assessments of changes in skin condition on day 84 and the average values for days 28, 56, and 84 of the study “Clinical and Instrumental Evaluation of the Effectiveness of the INSTYTUTUM Skincare Routine.”

INSTYTUTUM's Comprehensive Routine: 7 products. 8 steps. 84 days. Clinically proven results.
Clinical and Instrumental Assessment of the Effectiveness of the INSTYTUTUM Skincare Routine*
Depth of wrinkles in the “crow’s feet” area
Estimated biological age of the skin
Elasticity R2
Firmness R0
Standardized digital photographic documentation
Participants’ assessment of changes in skin condition
*Based on the results of the study “Clinical and Instrumental Evaluation of the Efficacy of the INSTYTUTUM Skincare Routine”: 84 days of daily use, 21 participants aged 35–60. The estimated biological age of the skin was determined based on the depth of periorbital wrinkles compared to reference data for women aged 30–65. Elasticity (R2) and firmness (R0) were assessed for the routine without Transforming Brightening Eye Cream. Individual results may vary.
84 days
of daily use of a comprehensive routine

21 participants
women aged 35–60

4 checkpoints
at the start, and after 28, 56, and 84 days
