*Based on an 84-day open-label clinical-instrumental study conducted under the supervision of a dermatologist at an independent European laboratory evaluating the full 7-product INSTYTUTUM AM/PM skincare routine (Adaptogel Cleanser, Resurfacing Glow Toner, Brightening Vitamin C Serum, X-Strength Retinol Serum, Sunscription Dark Spot Defence SPF50, Superbiotic Regenerating Cream, and Transforming Brightening Eye Cream, each applied as directed) among 21 female participants aged 35–60 (skin phototypes I–IV) with visible signs of chrono- and/or photo-ageing. The claimed reduction in calculated skin biological age reflects an average age equivalent derived solely from 3D profilometry measurements of periocular (crow’s feet) wrinkle depth compared to the testing laboratory’s reference correlation database for women aged 30–65. This constitutes an aesthetic calculation based on a single parameter, not a medical, biological, or comprehensive assessment of overall skin or bodily ageing. Individual results may vary; in the study, not all participants showed a reduction in periocular wrinkle depth. “Longevity Skincare” describes the product category and formulation approach of the INSTYTUTUM range and is not a claim of any effect on lifespan, cellular ageing, or physiological ageing processes. Full study documentation is available for regulatory authorities upon request. Individual results may vary. The photos are without any retouching. All results are from actual product use.