A revolution in skincare at-home by Longevity Scientists
Beautiful Now and Forever
INSTYTUTUM is transforming from a skincare brand into a longevity brand. We are evolving into future-driven skincare, designed to reduce biological age, because the skin is a reflection of the health of the entire body — an indicator, not the root cause of change. We focus on long-term quality of life management to help you live longer, healthier, and more energetic.





Dr. Natalia Bobok
For over 11 years, Natalia has been researching biological age as a key indicator of lasting beauty and exploring systemic approaches to healthy aging, long-term health, and longevity.
For over 11 years, Natalia has been researching biological age as a key indicator of lasting beauty and exploring systemic approaches to healthy aging, long-term health, and longevity.
Natalia Bobok (Ex Derkach)
Founder & CEO INSTYTUTUM, MD, PhD

INSTYTUTUM is transforming from a skincare brand into a longevity brand. We are evolving into future-driven skincare, designed to reduce biological age, because the skin is a reflection of the health of the entire body — an indicator, not the root cause of change. We focus on long-term quality of life management to help you live longer, healthier, and more energetic.
“Our mission is to simplify and accelerate the path to true, long-lasting beauty. No compromises, no ‘beauty on credit,’ and no short-term effects. We are creating a system that helps manage biological age by addressing both the causes and effects of aging—scientifically, safely, and for the long term.”
Natalia Bobok (Ex Derkach)
Founder & CEO INSTYTUTUM, MD, PhD



Dr. Natalia Bobok
For over 11 years, Natalia has been researching biological age as a key indicator of lasting beauty and exploring systemic approaches to healthy aging, long-term health, and longevity.
Longevity System by Dr. Natalia Bobok
We are currently developing a unique system. We will be introducing new product categories designed to help enhance beauty from within. We create products as part of a system designed to help women better understand and assess the skin’s biological age, with access to evidence-based information and skincare approaches guided by the key hallmarks of aging.

Longevity Next-Gen Line — INSTYTUTUM’s legendary skincare collection, designed to reduce the skin’s biological age*
INSTYTUTUM — Future-Driven Skincare designed to reduce the skin’s biological age*

Our formulas are backed by scientific research and contain targeted Longevity complexes with high concentrations of next-generation active ingredients and Inside & Out Technology, which works on three levels: cellular, tissue, and surface.
Due to their comprehensive action on these three levels, the formulas help address not only the effects but also the causes, and help prevent the appearance of aesthetic changes.
Unique, science-backed formulas help transform the skin at the cellular level, delivering impressive visible results and long-lasting skin health.
Inside
Out > Inside
Out


Inside
Out > Inside
Out
Age-Disrupting & Longevity Complex
A synergistic system of next-generation actives at high concentrations**, designed to reduce the skin’s biological age*
Help support key skin longevity mechanisms, including support of collagen, elastin, and hyaluronic acid synthesis***, antioxidant defense, and skin renewal
*Based on elasticity measurements obtained in an internal instrumental test using the Multi Skin Test Center MC 750, conducted over a three-month period in accordance with the manufacturer’s recommendations.
**Bobok, N.M.(2025). Should skincare products from different brands be combined for a systematic routine?
***Based on in vitro studies demonstrating increased collagen synthesis in dermal fibroblasts compared to control. Individual results may vary.
Adaptive Delivery Complex
(Humectants | Emollients | Occlusives)
A controlled delivery system that ensures optimal absorption, stability, and controlled delivery of active ingredients*
Enhances penetration without irritation or barrier overload, reduces transepidermal water loss (TEWL)
Designed to maximize efficacy while maintaining skin comfort and tolerance
*Controlled delivery is enabled by Sodium Retinoyl Hyaluronate (ester of hyaluronic and retinoic acids), which forms micelle-like structures supporting gradual penetration and controlled release of retinoid activity in the skin.
Barrier & Protection Complex
Restores and strengthens the epidermal barrier, optimizes hydration, and helps reduce skin sensitivity
Supports the skin’s adaptive capacity and helps maintain results over the long term
We focus on what helps reduce the skin’s biological age. Instead of dozens of products - minimalistic line of multifunctional hero products designed to address all skin concerns simultaneously. Less steps—more results.
Global Recognition
INSTYTUTUM is chosen by Hollywood stars, dermatologists, and cosmetologists in the U.S., Europe, and the Middle East for its fast, visible skin transformation results without compromise on safety.
Forbes USA named INSTYTUTUM the next disruptor in the skincare industry.
11 years of research
Each formula is developed in Switzerland by a team of the world’s leading doctors and longevity scientists.
Brand History
Brand History
Sustainability
We create highly efficient skincare products, combining with a deep care for the planet.

Future-Driven Skincare designed to reduce the skin’s biological age*
*Based on elasticity measurements obtained in an internal instrumental test using the Multi Skin Test Center MC 750, conducted over a three-month period in accordance with the manufacturer’s recommendations.